In Kanazawa, Japan, a recent study by researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, published in ACS Nano on September 12, 2025, reveals a groundbreaking discovery. The research highlights the controllable activation of proteins within cells through heating. This method showcases the potential for utilizing heat to trigger programmed cell death. This innovative approach introduces new possibilities in cellular research and holds promise for various applications involving cell manipulation.